This study is aimed on Magnetic resonance imaging (MRI) modalities for monitoring Herceptin (trastuzumab) efficacy in breast cancer cells ex vivo. The efficacy...
Journal of Pharmaceutical and Biomedical Analysis, 11 mars 2010, Volume : 51, Numéro : 4
The aim of this study was to assess the Herceptin efficacy in ex vivo cultures of MCF-7 breast carcinoma cells. Herceptin was used with perfluorooctyl bromide...
Archives of Biochemistry and Biophysics, 15 janvier 2010, Volume : 493, Numéro : 2
The cellular monitoring of tumor response to treatments is important for drug discovery and drug development in cancer therapy. We studied efficacy of...
We studied two human mammary carcinoma cell lines, MCF-7(NEO-4) HER-2 negative and MCF-7(HER-2) HER-2 positive, in three-dimensional culture. The aim of the...
Journal of Pharmaceutical and Biomedical Analysis, 2 novembre 2010, Volume : 53, Numéro : 3
Oximetry of the human T-Lymphoblastoid (CEM) cells was measured using 19F magnetic resonance imaging (19F MRI). The cells were treated with the analogues of...
Journal of Pharmaceutical and Biomedical Analysis, 7 septembre 2010, Volume : 51, Numéro : 5
The effective targeting of malignant cell surface antigens is essential in cancer therapy. Resistance to treatment and rapid invasion of cancer cells are the...
Biomedicine&Pharmacotherapy, 11 mars 2010, Volume : 64, Numéro : 6
This study was aimed at the applications of an ex vivo assays to characterization of CEM (Human T-Lymphoblastoid) cells. CEM cells were cultured in three...
Journal of Proteome Research, 5 mars 2010, Volume : 9, Numéro : 3
The humanized monoclonal antibody IgG1 in combination with chemotherapy has been demonstrated to enhance survival benefit in cancer treatment. Despite positive...
Haloperidol is a commonly used neuroleptic drug associated with a range of side effects. The aim of the study was to determine in vitro interaction of...
The therapeutic humanized monoclonal antibody IgG1 known as Herceptin has shown remarkable antitumor effects. Although this type of therapy has increased the...
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